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Preparation of Bromoketone: The synthesis often commences While using the manufacture of an α-bromoketone through the corresponding arylketone.
Nucleophilic Substitution: This bromoketone undergoes nucleophilic substitution using an suitable amine, frequently methylamine, to generate the ultimate product or service.
Solubility: Sparingly soluble in phosphate-buffered saline; a little soluble in ethanol and dimethyl sulfoxide
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Crystallography:3-Methylethcathinone hydrochloride crystallizes in ionic lattices stabilized by N–H⁺···Cl⁻ hydrogen bonds and weaker interactions like C–H···Cl⁻ and C–H···O=C. These interactions generate attribute supramolecular motifs observable via X-ray diffraction. Although precise crystal parameters for three-MEC HCl are limited inside the literature, its structural analog methylone hydrochloride (MDMC·HCl) delivers a reference: it adopts a monoclinic P2₁/c House group with well known N–H⁺···Cl⁻ contacts (~2.
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